Scientific Research

Analytical Rigour.
Reproducible Results.

Our research programme covers alkaloid profiling, extraction optimisation, stability studies and bioactivity assessment — all conducted or verified by accredited independent laboratories across Europe.

Analytical Methodology

How We Verify Every Batch

A six-stage quality pipeline ensures that every product leaving our facility has been independently verified for identity, purity, potency and absence of contaminants.

01

Plant Identification

Morphological and molecular verification of T. iboga versus related species before processing begins.

02

Extraction & Fractionation

Standardised ethanol extraction followed by acid-base partition to isolate total alkaloid fraction.

03

HPLC-DAD Analysis

High-performance liquid chromatography with diode-array detection quantifies ibogaine, noribogaine, tabernanthine and 12 minor alkaloids.

04

Heavy Metals Screening

ICP-MS analysis for lead, mercury, cadmium and arsenic against European Pharmacopoeia limits.

05

Microbial Testing

Total aerobic count, yeast/mould, E. coli and Salmonella tested per EP 2.6.12 criteria.

06

Certificate of Analysis

Full CoA issued by accredited ISO 17025 laboratory. Downloadable from each product page.

Research Areas

Current Focus Areas

Our research collaborations with European universities and independent institutes address both fundamental phytochemistry and applied pharmacology.

Alkaloid Profiling

Comprehensive mapping of the 17 known iboga alkaloids across different chemotypes, harvest regions and processing methods. Building the most extensive ibogaine congener database in Europe.

Extraction Optimisation

Systematic evaluation of solvent systems, temperature gradients and filtration protocols to maximise alkaloid yield while minimising co-extracted impurities.

Stability Studies

ICH Q1A-compliant accelerated and long-term stability testing to establish shelf life and appropriate storage conditions for each product format.

Bioactivity Assessment

Collaboration with two European pharmacology institutes to characterise receptor-binding profiles and in-vitro cytotoxicity thresholds for primary alkaloid fractions.

Ethnobotanical Mapping

Fieldwork in Gabon and Cameroon documenting traditional preparation methods, dosage knowledge and ceremonial contexts — preserving cultural IP alongside scientific data.

Regulatory Dossier Development

Building EU Article 16(d) traditional-use dossiers to support future registration pathways for standardised iboga preparations.

Publications & Data

Selected Research Outputs

Peer-reviewed publications, conference proceedings and internal technical reports available to registered researchers.

2024
Journal of Natural Products Peer-reviewed
Alkaloid Congener Ratios as Chemotypic Markers in Tabernanthe iboga: A Pan-European Comparative Study
Van der Meer E., Renard I., Bauer K.
2023
Phytochemistry Letters Peer-reviewed
Optimised HPLC-DAD Method for Simultaneous Quantification of Twelve Iboga Alkaloids in Commercial Preparations
Van der Meer E., Hoffmann S.
2023
EIHA Conference Proceedings Conference paper
CITES Compliance and Sustainable Harvesting Frameworks for Tabernanthe iboga in Central Africa
Diallo A., Renard I.
2022
Internal Technical Report Available on request
ICH Q1A Stability Data for Ibogaine HCl Reference Standards: 24-Month Accelerated Study Results
Iboga Culture R&D Team
Laboratory Partners

Independent Verification Network

We do not rely on in-house testing alone. Every product is verified by at least one ISO 17025-accredited laboratory from our independent partner network.

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Netherlands

ISO 17025-accredited analytical laboratory. Primary partner for HPLC-DAD and ICP-MS analysis.

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Switzerland

Specialised in pharmacopoeial identity testing and European Pharmacopoeia compliance verification.

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Germany

Microbial testing and mycotoxin screening. COFRAC-equivalent DAkkS accreditation.

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France

Bioactivity and receptor-binding studies conducted in partnership with a Lyon pharmacology institute.

Request Analytical Documentation

CoAs, stability reports and methodology summaries are available to registered researchers and licensed practitioners.